Potassium is the primary intracellular cation — 98% of body potassium is inside cells, creating the electrical gradient essential for nerve impulses, muscle contractions, and cardiac rhythm. For blood pressure, potassium works through: (1) increasing renal sodium excretion (natriuresis) — directly countering sodium's hypertensive effect; (2) vasodilation via endothelial nitric oxide; (3) reducing sympathetic nervous system activity. The sodium:potassium ratio in the diet is now considered more important than absolute sodium intake — high potassium blunts the BP-raising effect of sodium.
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.