What is the recommended dose of Iodine?

- **Look for:** Potassium iodide, 150-200mcg per tablet, clearly labeled dose; iodine from kelp ONLY if standardized and dose-verified by third party - **Avoid:** Unstandardized kelp/seaweed supple...

Is Iodine safe to take daily?

Iodine is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

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Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Iodine

MODERATE EVIDENCEMineralLast updated

AVELOR SUMMARY

Iodine is essential for thyroid hormone synthesis — without it, you cannot produce T3 or T4. Our research shows that while overt deficiency (goiter, cretinism) is rare in iodized-salt countries, suboptimal iodine status is surprisingly common, particularly in pregnant women where even mild deficiency reduces child IQ by 6-10 points. The critical safety concern: both deficiency AND excess cause thyroid dysfunction. Supplementing >1,100mcg/day (the UL) can trigger thyroid autoimmunity, hypothyroidism, or hyperthyroidism — especially in populations with pre-existing thyroid disease. This is a supplement where more is definitively NOT better.

WHAT IT DOES

Iodine is the essential substrate for thyroid peroxidase (TPO), the enzyme that incorporates iodine into thyroglobulin to form T4 (thyroxine) and T3 (triiodothyronine). Without iodine, TPO has nothing to work with and thyroid hormone production stops. The thyroid gland actively concentrates iodine 20-50x above blood levels via the sodium-iodide symporter (NIS). In deficiency, the gland enlarges (goiter) trying to capture more iodine. In excess, the Wolff-Chaikoff effect temporarily halts hormone production, but chronic excess can permanently damage the gland, especially in those with anti-TPO antibodies (Hashimoto's).

OPTIMAL DOSAGE

Look for: Potassium iodide, 150-200mcg per tablet, clearly labeled dose; iodine from kelp ONLY if standardized and dose-verified by third party
Avoid: Unstandardized kelp/seaweed supplements (iodine content is wildly variable); Lugol's solution or SSKI for routine supplementation; any product providing >500mcg per serving without medical indication
Minimum effective dose: 150mcg/day for adults; 220mcg/day for pregnant women
Third-party tested brands: Life Extension, Thorne (both potassium iodide, labeled accurately)

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SAFETY PROFILE

Critical Interactions (Do Not Combine Without Medical Supervision)

Moderate Interactions (Monitor Closely)

Theoretical/Low-Risk Interactions

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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