Vitamin K2 (MK-4 and MK-7) activates osteocalcin (bone) and matrix-Gla protein (anti-vascular calcification). MK-7 has a 72-hour half-life (vs MK-4's 1-2 hours) — one daily dose maintains steady levels. The Rotterdam Study: highest K2 intake → 50% reduction in arterial calcification, 50% reduction in cardiovascular death. 90-200μg/day MK-7. MenaQ7® is the gold-standard branded MK-7 with the most clinical data. for the synergistic combination. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.