Hypericum perforatum — equivalent to SSRIs for mild-moderate depression (Linde 2008 Cochrane review). CRITICAL DRUG INTERACTIONS: PXR/CYP3A4 induction reduces effectiveness of OCPs, warfarin, HIV drugs, immunosuppressants, many more. The most dangerous herb for drug interactions in the entire supplement industry. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.