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Reviewed by the Scan Dose Research Team and Clinical Advisory Board

Shatavari

MODERATE EVIDENCEBotanicalLast updated

SCAN DOSE SUMMARY

Shatavari is the premier Ayurvedic female reproductive tonic — its Sanskrit name means "she who has a hundred husbands" (referencing fertility/vitality). Our research shows shatavari contains steroidal saponins (shatavarins) that have galactagogue (breast milk production), adaptogenic, and phytoestrogenic activity. A 2016 RCT found it increased prolactin levels by 33% in breastfeeding mothers. The herb also has genuine antioxidant and gastroprotective effects (protects gastric mucosa comparably to ranitidine in animal models). Clinical evidence in humans is growing but still limited — most studies are small Indian trials.

WHAT IT DOES

Shatavarins (steroidal saponins): (1) increase prolactin secretion from anterior pituitary — possibly by modulating dopaminergic tone (dopamine inhibits prolactin; shatavari may reduce dopamine's inhibitory effect); (2) phytoestrogenic — bind ERα and ERβ with moderate affinity, providing mild estrogenic support for reproductive tissues; (3) adaptogenic — modulate HPA axis cortisol response; (4) gastroprotective — increase gastric mucus secretion and prostaglandin E2 production (protective), while reducing acid secretion; (5) antioxidant — direct free radical scavenging and SOD enhancement; (6) immunomodulatory — enhance macrophage activity and IL-1 production.

OPTIMAL DOSAGE

  • Look for: Asparagus racemosus root extract; standardized to saponins/shatavarins; 500-1,000mg per serving; organic
  • Avoid: Aerial parts (not root); non-standardized; Western asparagus (different species entirely)
  • Minimum effective dose: 500mg root extract/day
  • Third-party tested brands: Himalaya, Organic India, Banyan Botanicals
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SAFETY PROFILE

Moderate Interactions (Monitor Closely)

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Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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