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Reviewed by the Scan Dose Research Team and Clinical Advisory Board

Methylcobalamin

MODERATE EVIDENCEVitaminLast updated

SCAN DOSE SUMMARY

Methylcobalamin is the active coenzyme form of B12 (vs cyanocobalamin which must be converted). Better retained by tissues than cyanocobalamin. 1,000-5,000μg sublingual for deficiency correction. CRITICAL for: vegans (zero dietary B12), elderly (reduced intrinsic factor), metformin users (depletes B12), PPI users (reduced absorption). Hydroxocobalamin injection is preferred for severe deficiency. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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