What is the recommended dose of Fenugreek?

- **Blood sugar:** 5-50g/day seed powder with meals, or 500-1,000mg extract - **Testosterone/libido:** 500-600mg/day Testofen (standardized to 50% fenuside) - **Lactation:** 500-1,000mg 3x/day seed...

Is Fenugreek safe to take daily?

Fenugreek is rated "Prescription Interactions" based on clinical evidence. - GI effects: bloating, gas, diarrhea (due to fiber content) - Maple syrup body odor and urine odor (sotolone compound — harmless but notable) - Possible allergic reaction in legume-allergic individuals (peanut, chickpea cros

Does Fenugreek interact with any medications?

Fenugreek has 3 known drug interactions, including interactions with Insulin / diabetes medications, Warfarin, Theophylline. Check with your doctor before combining with prescription medications.

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Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Fenugreek

MODERATE EVIDENCEBotanicalLast updated April 2026

AVELOR SUMMARY

Fenugreek is a legume with evidence across an unusually wide range of conditions: blood sugar control, testosterone support, lactation enhancement, and libido improvement. Our research shows the glucose-lowering effect is the strongest — driven by galactomannan fiber and 4-hydroxyisoleucine. The testosterone claims are more nuanced: fenugreek may increase free testosterone by inhibiting aromatase and 5-alpha reductase, but total testosterone effects are modest.

EVIDENCE GRADES

Blood sugar reduction (T2D)Moderate — multiple RCTs (PMID: 24393738)

Testosterone / libido (men)Moderate — several positive trials (PMID: 21312304)

B-

Lactation (galactagogue)Moderate — traditional + limited clinical support

B-

Lipid profile improvementModerate — small consistent effects

C+

Exercise performanceLimited evidence

OPTIMAL DOSAGE

Blood sugar: 5-50g/day seed powder with meals, or 500-1,000mg extract
Testosterone/libido: 500-600mg/day Testofen (standardized to 50% fenuside)
Lactation: 500-1,000mg 3x/day seed powder or 580-610mg capsules 3x/day
Lipid support: 10-100g/day seed powder (high dose due to fiber mechanism)
Take with meals for blood sugar effects (fiber mechanism)

Scan a supplement containing Fenugreek

DRUG INTERACTIONS

Insulin / diabetes medicationsSevere

Additive blood sugar lowering → hypoglycemia risk

WarfarinModerate

Fenugreek contains coumarin compounds; may increase bleeding risk

TheophyllineModerate

May decrease theophylline absorption

SAFETY PROFILE

Drug Interactions

Side Effects

GI effects: bloating, gas, diarrhea (due to fiber content)
Maple syrup body odor and urine odor (sotolone compound — harmless but notable)
Possible allergic reaction in legume-allergic individuals (peanut, chickpea cross-reactivity)
May cause uterine contractions at high doses

Pregnancy & Lactation

Pregnancy: AVOID — Traditional abortifacient at high doses. Oxytocic properties documented. (PMID: 21120041)
Lactation: Traditional galactagogue. Limited clinical evidence supports use postpartum for milk production. Generally considered safe during breastfeeding.

WADA Status

Not Prohibited

HOW AVELOR SCORES THIS

Testofen (standardized extract) scores highest for testosterone applications

Raw seed powder: scores well for blood sugar but requires high doses

Diabetes medication users: automatic hypoglycemia warning

Pregnancy: automatic contraindication flag

Maple syrup odor disclosure: harmless but include in user guidance

Legume allergy cross-reactivity warning

CLINICAL REFERENCES

Neelakantan N et al. Effect of fenugreek on glycemia: a meta-analysis of clinical trials.

PMID: 24393738

Steels E et al. Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract.

PMID: 21312304

Yadav UC, Baquer NZ. Pharmacological effects of Trigonella foenum-graecum.

PMID: 21120041

Gupta A et al. Effect of Trigonella foenum-graecum on blood glucose levels in type 2 diabetes.

PMID: 15507277

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated: April 2026

Not medical advice. Based on published clinical research and systematic reviews.

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