Evodiamine is a thermogenic compound from the Chinese herb Evodia that activates TRPV1 (vanilloid receptor — same as capsaicin) to increase core body temperature and energy expenditure. In vitro data shows fat cell apoptosis and anti-obesity effects. ZERO human clinical trials exist. Sold in fat-burner supplements but no established human dose. Our assessment: promising mechanism, zero human evidence. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.