Ursolic Acid

Ursolic acid (from apple peels, holy basil, rosemary) is a pentacyclic triterpenoid that increases muscle mass while decreasing fat mass — a 'recomposition' compound. In 2012, University of Iowa researchers showed ursolic acid activates Akt/mTOR (muscle growth) while simultaneously activating brown fat thermogenesis. Animal data is strong: reduced obesity, increased muscle, improved insulin sensitivity. Human clinical trials are just beginning. Found in apple peels (80mg per apple), rosemary, and tulsi. Supplemental dose: 150-450mg/day. The 'eat the apple peel' advice is literally evidence-based. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*