Is Theacrine safe to take daily?

Theacrine is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Theacrine

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Theacrine is structurally similar to caffeine but acts on BOTH adenosine receptors (like caffeine) AND dopamine receptors (unlike caffeine). The result: stimulation without tolerance development. A 2016 study found 300mg/day theacrine for 8 weeks did NOT produce tolerance (unlike caffeine which develops tolerance in 5-10 days). Also: no habituation, no withdrawal, no BP increase. TeaCrine® (Compound Solutions) is the branded form. Found naturally in kucha tea (Camellia kucha). Dose: 100-300mg/day. Synergistic with caffeine (enhances and extends caffeine's effects). --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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