Dynamine® (methylliberine) from sorghum is a purine alkaloid structurally similar to caffeine and theacrine but with FASTER onset and SHORTER duration — 'the espresso shot of nootropics.' Acts on adenosine and dopamine receptors. Does NOT increase BP or HR in preliminary data. Onset: 15-30 minutes. Duration: 1-3 hours (vs caffeine's 5-6 hours). Dose: 100-200mg. No tolerance development reported. Often stacked with TeaCrine® for extended duration. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.