Silibinin is the most active component of milk thistle's silymarin complex. 420-600mg/day silymarin for liver protection. IV silibinin (Legalon SIL®) is the ONLY approved treatment for Amanita mushroom (death cap) poisoning — it blocks hepatocyte toxin uptake. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.