Is Pygeum safe to take daily?

Pygeum is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Pygeum

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

African plum bark extract for BPH — a Cochrane review (18 RCTs, 1,562 men) found pygeum reduced nighttime urination by 19%, improved urine flow, and reduced residual volume. Contains beta-sitosterol and pentacyclic triterpenes (ursolic acid) that inhibit 5-alpha reductase and have anti-inflammatory effects in prostate tissue. Dose: 100-200mg/day standardized extract. Often combined with saw palmetto (Permixon® + Tadenan® combination used in European urology). --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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