Is Polypodium Leucotomos safe to take daily?

Polypodium Leucotomos is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Polypodium Leucotomos

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Central American fern extract with STRONG evidence as an oral sunscreen supplement. Fernblock® (480mg before sun exposure) reduced sunburn by 63% and UV-induced DNA damage by 84%. The mechanism: PLE's antioxidants and anti-inflammatory compounds are distributed to skin after oral absorption, providing systemic photoprotection. Used by dermatologists as adjunct for sun-sensitive skin conditions (polymorphous light eruption, vitiligo). Does NOT replace topical sunscreen but adds an 'internal SPF layer.' Dose: 240-480mg 30 min before sun exposure. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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