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Reviewed by the Scan Dose Research Team and Clinical Advisory Board

Policosanol

MODERATE EVIDENCESupplementLast updated

SCAN DOSE SUMMARY

Policosanol (from sugarcane wax) was reported by Cuban researchers to reduce LDL by 20-25% — rivaling statins. Then EVERY independent replication FAILED. A 2006 German study, a 2002 Dutch study, and a 2006 Canadian study ALL found zero cholesterol effect. Our assessment: the Cuban data is unreliable — likely publication bias or methodological issues specific to that one research group. Not recommended for cholesterol management despite continued marketing. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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