What is the recommended dose of PeakO2®?

- **Look for:** PeakO2® brand (Compound Solutions); 4g per daily dose; all 6 mushrooms listed - **Avoid:** Generic "6 mushroom blends" (not PeakO2 formulation); underdosed (<4g/day); mycelium-on-gr...

Is PeakO2® safe to take daily?

PeakO2® is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

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Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

PeakO2®

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

PeakO2 is a patented blend of 6 adaptogenic mushrooms (Cordyceps militaris, Reishi, King Trumpet, Shiitake, Lion's Mane, Turkey Tail) designed for exercise performance. A 2017 study at the University of North Carolina found 4g/day for 21 days increased VO2max by 7% and time to exhaustion by 70 seconds. Our research shows this is ONE study from ONE group — promising but far from definitive. The blend approach makes it impossible to attribute effects to any single mushroom. Cordyceps (the primary active for exercise) has its own monograph with stronger standalone evidence.

WHAT IT DOES

Proposed mechanisms from individual mushroom components: (1) Cordyceps militaris — cordycepin enhances mitochondrial ATP production and oxygen utilization; (2) Reishi — triterpenes modulate cortisol response (adaptogenic); (3) Lion's Mane — NGF stimulation (cognitive under fatigue); (4) Turkey Tail — beta-glucan immune support during heavy training; (5) Shiitake — eritadenine cardiovascular support; (6) King Trumpet — ergothioneine antioxidant. The combination is hypothesized to address multiple exercise-limiting factors simultaneously.

OPTIMAL DOSAGE

Look for: PeakO2® brand (Compound Solutions); 4g per daily dose; all 6 mushrooms listed
Avoid: Generic "6 mushroom blends" (not PeakO2 formulation); underdosed (<4g/day); mycelium-on-grain fillers
Third-party tested brands: Momentous, PEScience, KSM (PeakO2 ingredient)

Scan a supplement containing PeakO2®

SAFETY PROFILE

See individual mushroom monographs (cordyceps.md, reishi.md, lions-mane.md, turkey-tail-mushroom.md). Primary concern: Reishi has blood-thinning properties.

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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