Is NADH safe to take daily?

NADH is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

NADH

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

NADH is the reduced (electron-carrying) form of NAD+ — the coenzyme involved in 400+ metabolic reactions. A 2004 study found 5-20mg/day NADH reduced fatigue in chronic fatigue syndrome by 31%. Also: improved jet lag recovery in a small crossover trial. The concern: oral NADH stability is poor (degrades rapidly in stomach acid). Enteric-coated ENADA® is the stabilized form used in studies. Dose: 5-20mg/day on empty stomach. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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