0.3-0.5mg is the physiological dose (most products are 10-30x overdosed). Higher doses (3-5mg) work for jet lag and shift work. Extended-release for sleep maintenance (staying asleep); immediate-release for sleep onset (falling asleep). Circadin® (2mg extended-release) is the EU-approved form. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Based on independent third-party laboratory analysis
Category pass rate: ~85% pass rate. Primary issue: massive dose variation (up to 478% between highest/lowest variance products). Gummies tend to have higher variance than pills.
Melatonin reduces time to fall asleep by 12-17 minutes only (not hours); Does NOT improve sleep quality or total sleep time; Lower doses (0.3-1mg) are as effective as higher doses for sleep onset; Higher doses are NOT more effective — they just increase side effects
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.