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Reviewed by the Scan Dose Research Team and Clinical Advisory Board

I3C

MODERATE EVIDENCESupplementLast updated

SCAN DOSE SUMMARY

Cruciferous vegetable compound that shifts estrogen metabolism toward protective 2-OHE1. DIM (diindolylmethane) is preferred over I3C for supplementation — more predictable conversion, avoids ICZ (AhR agonist) formation in stomach. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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