Dong quai is called "female ginseng" in traditional Chinese medicine and is one of the most widely used herbs for menstrual and menopausal complaints in Asia. Our research shows the clinical evidence does NOT support its use as a standalone treatment — the only rigorous RCT found it was no better than placebo for menopausal symptoms. It contains coumarins with anticoagulant activity and furanocoumarins that cause photosensitivity. Its primary risk is bleeding when combined with anticoagulants.
Dong quai contains three pharmacologically active compound classes: (1) phthalides (ligustilide, butylphthalide) — smooth muscle relaxants that may relieve menstrual cramps; (2) coumarins — natural blood thinners that inhibit platelet aggregation; and (3) ferulic acid — an anti-inflammatory and antioxidant. In TCM theory, it "nourishes blood" and "invigorates circulation." The coumarin content is the primary safety concern — it genuinely affects clotting.
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.