Diosmin is a citrus flavonoid with STRONG evidence for chronic venous insufficiency and hemorrhoids. Daflon® 500 (90% diosmin + 10% hesperidin, micronized) is one of the most prescribed venous medications in Europe — prescribed to 30M+ patients. A 2005 Cochrane review confirmed it significantly reduces CVI symptoms. Reduces venous inflammation via leukocyte adhesion inhibition. Dose: 500mg 2x/day or 1,000mg once daily. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.