Caralluma is an Indian cactus traditionally used as a famine food to suppress hunger. A 2015 meta-analysis found Caralluma extract (500-1,000mg/day) significantly reduced waist circumference by 2.7 cm and appetite vs placebo. The mechanism involves hypothalamic appetite center modulation — pregnane glycosides block hunger signaling. Slimaluma® is the branded extract. Dose: 500mg 2x/day before meals. Effect size is modest but consistent. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Reviewed by the Scan Dose Research Team and Clinical Advisory Board | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.